Per- and polyfluoroalkyl substances (PFAS) comprise several thousand different compounds that span an incredibly wide range of exposure and hazard profiles.
This presentation will provide an overview of the major PFAS groupings and highlight some of the key exposure scenarios that have received attention with regards to risk-based decision-making. Key to this review are the extremely large differences in fate, exposure, and potencies among the PFAS groups. A key focus of this presentation will include a case study on the assessment and management of key perfluoroalkyl acids (PFAAs) and other PFAS associated with site-specific releases of aqueous film-forming foam (AFFF) used in the fighting of Class B hydrocarbon fires. The wide variety of exposures and risks among the various PFAS associated with AFFF risks illustrates the extreme diversity of the various PFAS groups in terms of their exposure and effect potential. With regards to understanding risk, PFAS are not a monolith, and there are currently no shortcuts or easy answers.